Driven by the development of innovative electrode materials, the brain-machine interface (BMI) NUTRI B12 has witnessed significant advancements in recent years.However, traditional implantable electrodes, such as metal-based and polymer-based electrodes, often face limitations in terms of flexibility, chronic stability, and long-term biocompatibili
Multiple virtual screening approaches for finding new Hepatitis c virus RNA-dependent RNA polymerase inhibitors: Structure-based screens and molecular dynamics for the pursue of new poly pharmacological inhibitors
Abstract The RNA polymerase NS5B of Hepatitis C virus (HCV) is a well-characterised drug target with an active site and four allosteric binding sites.This work presents a workflow for virtual screening and its application to Drug Bank screening Travel Fee targeting the Hepatitis C Virus (HCV) RNA polymerase non-nucleoside binding sites.Potential po
A Simple Photonics-Based Measurement Method for Microwave DFS and AOA
This article put forwards a simple microwave photonics measurement method for microwave doppler frequency shift (DFS) and angle of arrival (AOA), which obtains the information conveniently and precisely by comparing the frequency and phase shift between two channels signals.The DFS direction can be judged more intuitively thanks to Cable Saver the
Physical Consistent Path Planning for Unmanned Surface Vehicles under Complex Marine Environment
The increasing demand for safe and efficient maritime transportation has underscored the necessity of developing effective path-planning algorithms for Unmanned Surface Vehicles (USVs).However, the inherent complexities of the ocean environment and the non-holonomic Hair spray properties of the physical system have posed significant challenges to d
The role of TET proteins in stress-induced neuroepigenetic and behavioural adaptations
Over the past decade, critical, non-redundant Oven Fan Element roles of the ten-eleven translocation (TET) family of dioxygenase enzymes have been identified in the brain during developmental and postnatal stages.Specifically, TET-mediated active demethylation, involving the iterative oxidation of 5-methylcytosine to 5-hydroxymethylcytosine and sub